The MRes Cardiovascular Health and Disease course at the University of Manchester promotes cardiovascular research within a unique multi-disciplinary training environment. The programme aims to equip students with broadly based biomedical research skills, but with an emphasis on application to cardiovascular science.
Cardiovascular diseases are responsible for considerable mortality, disability and a reduced quality of life in the developed world. Despite the large number of treatment strategies, the widespread occurrence of these disorders dictates the search for improved treatments. The development of these relies on a continued evolution of our understanding of the underlying mechanisms responsible for the development of cardiovascular disorders.
It is now widely recognised by employers and research councils that unravelling the basis of cardiovascular disease and development of new therapies is a high priority area for investment especially since the economic burden of CVD is increasing. It is also recognised, however, that a gap has opened up between the skills possessed by new graduates and the skills normally expected on entry to a research degree or an industrial research career. The MRes in Cardiovascular Health and Disease has been specifically designed to fill this gap for those who wish to pursue a research career in cardiovascular sciences.
Additional course information
Prof Mark Boyett
Dr Elizabeth Cartwright
Dr Kat Dibb
Dr Halina Dobrzynski
Prof David Eisner
Dr Adam Greenstein
Prof Tony Heagerty
Dr Cathy Holt
Dr Ashraf Kitmitto
Dr Delvac Oceandy
Dr Jaqui Ohanian
Dr Vasken Ohanian
Prof Andrew Trafford
Dr Luigi Venetucci
Research topic examples:
Coronary arterial contractility and endothelial function
Sick sinus syndrome and gene therapy
Can we un-stiffen arteries?
Cellular basis of cardiac arrhythmias
Elucidation of the pathogenesis of atherosclerosis
The role of oxidative stress and channelopathies in heart failure
Mechanisms of diabetic cardiomyopathy
Cell signalling in vascular smooth muscle
Cellular dysfunction and EC remodelling in heart disease and ageing
Development of a novel therapeutic approach to cardiac hypertrophy and heart failure
Coursework and assessment
Assessment is through a combination of written reports (in journal style format), literature review, problem based learning (PBL) tutorials and oral presentations.
This range of training methods aims to promote a stimulating and dynamic learning environment. The different course units will enable the development of key transferable skills in critical analysis of research methodologies, data interrogation, communication and time management.
Course unit details
The programme is designed to provide the students with:
A specialist knowledge of the principles of the cardiovascular system in health and disease with an emphasis on emerging technologies (taught lectures)
Laboratory skills, research methodology and data analysis (two research projects)
Critical analysis of scientific and medical literature (lit. review)
Intellectual skills for understanding and interpreting research problems (tutorials)
Communication of scientific data and concepts (oral presentations and written reports)
The programme comprises the following compulsory components:
Faculty Research Methods Unit (15 credits)
Taught seminar unit (15 lectures, 2h each) (15 credits)
Module 1: Vascular science
Module 2: Cardiac science
Module 3 : From bench to bedside - therapeutic strategies for combating cardiovascular disease
Tutorial course unit (15 credits)
Practical Skills unit (15 credits)
Research Project 1: Literature review and grant / fellowship proposal (30 credits)
Research project 2: Laboratory/clinical based project (January- July). Written up a research paper with a short oral presentation of results (90 credits).
Clinical Masterclass course unit:
The Clinical Masterclass course unit is a 15 credit unit specifically designed for intercalated medical students. The unit consists of a series of seminars, workshops and e-learning.
This unit contributes to personal and professional development in the experience, knowledge and skills training required for effective clinical practice and success, with a strong emphasis on clinical academic research.
Areas covered include:
advanced Good Clinical Practice (GCP)
research governance and the regulatory framework for research
the Human Tissue Act
practical clinical ethics
patient and public involvement in research
diversity/equal opportunities in research/cultural competence
research creativity and entrepreneurialism
leadership (Practitioner, Partner and Leader roles)
Course unit list
The course unit details given below are subject to change, and are the latest example of the curriculum available on this course of study.TitleCodeCredit ratingMandatory/optional
Practical Skills Unit
Principles of the Cardiovascular System in Health and Disease
IMPORTANT NOTE: Per 6 April 2015 only the English language tests from IELTS and Trinity College London are accepted for Tier 4 Visa applications to the United Kingdom. Other tests (including TOEFL, TOEIC, Pearson, City & Guilds) are no longer accepted for Tier 4 visa applications to the United Kingdom. The university might still accept these tests to admit you to the university, but if you require a Tier 4 visa to enter the UK and begin your degree programme, these tests will not be sufficient to obtain your Visa. Since the Trinity College London language tests must be taken in one of their exam centres in the UK, IELTS is now the only language test accepted for Tier 4 visas to the UK that can be taken worldwide.
The course is open to medical or science graduates and intercalating medical students. Candidates are selected from the students admitted to the MBChB undergraduate course of The University of Manchester. The minimum criterion for admission is satisfactory achievement in years 1 to 3/4 of the undergraduate medical programme.
For University of St Andrews students, this includes their three-year degree programme and the following one or two years spent in Manchester (years 3 and 4 of the Manchester programme).
We also accept intercalating medical students from other UK Universities including home medical and dental graduates and international medical graduates who can demonstrate relevant experience and commitment to biomedical research.
Normally a BSc (1st or 2:1, though under exceptional circumstances candidates with a 2:2 will be considered), MBChB or equivalent is expected from a British university in an appropriate biological or medical subject. International candidates must have obtained the equivalent of a 2:1 in a related degree from a reputed University.
Most international students must demonstrate English proficiency through a secure and approved testing system, such as IELTS or TOEFL. International students should refer to entry requirements for your country . We require a minimum of:
IELTS 6.5 overall with 6.0 in writing
577 paper-based (TWE* - 6.0)
233 computer-based (TWE* - 6.0)
90 internet-based (with 22 in each component)
* TWE - Test of Written EnglishSome English language test results are only valid for two years. Your English language test report must be valid on the start date of your course.
No work experience is required.
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